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    E.g., 16/08/2022
    E.g., 16/08/2022
    Imagen de histología que muestra la comparación del tamaño del corazón de un ratón normal (izquierda) y un ratón deficiente para la proteína MKK6 (derecha).
    Research
    9 Aug 2022
    eLife: CNIC scientists uncover opposing roles of p38 proteins in cardiac hypertrophy

    A new study published in eLife shows that inhibition of p38γ/δ is a potential therapeutic strategy for the treatment of hypertrophic cardiomyopathy, but that this strategy has yet to be explored because of the lack of specific inhibitors for these p38 family members
    La Dra. Amelia Escolano
    About the CNIC
    9 Aug 2022
    "CNIC is like an oasis for science in Spain"

    Dr. Amelia Escolano runs her own group in Philadelphia (USA) where she is an Assistant Professor at the Wistar Institute's Center for Vaccines and Immunotherapy
    Microfotografía de una monocapa de cardiomiocitos derivados de células madre inducidas a la pluripotencia, representativa de las que se usaron para estudiar los mecanismos de arritmias y el rescate de la función normal por el gen que codifica a la sintrofina-α
    Research
    29 Jun 2022
    eLife: Study reveals how Duchenne muscular dystrophy causes heart rhythm problems

    Investigadores del CNIC  revelan por primera los mecanismos moleculares que subyacen a las arritmias que ocurren en pacientes que padecen “Distrofia Muscular de Duchenne”
    Juan Domingo Gisbert
    About the CNIC
    24 Jun 2022
    Juan Domingo Gisbert: "Combining CNIC and BBRC data will allow us to answer questions of great relevance for the prevention of Alzheimer's in healthy subjects"

    Juan Domingo Gispert López, head of the Barcelonaβeta Brain Research Center and CNIC (Spanish National Centre for Cardiovascular Research) researcher
    Marta Cortés Canteli teams
    About the CNIC
    18 May 2022
    The BrightFocus Foundation grants an Alzheimer’s Disease Research Standard Award to a CNIC project

    The project will examine long-term changes in plasma biomarkers of neuronal injury, neuroinflammation, and Alzheimer's disease in participants in the PESA-CNIC-SANTANDER study who have undergone imaging studies to map brain metabolism. The goal of the project is to determine how cardiovascular risk factors during midlife impact brain function
    An optical section from a ventral view of a mouse embryo at embryonic day E8.0. The section is overlain with a cast of the three-dimensional shape of the forming heart (red) and the incipient circulatory system (purple).
    Research
    17 May 2022
    Nature Cardiovascular Research: A CNIC team creates a dynamic 3D atlas of the formation of the embryonic heart

    The 3D atlas has allowed the scientists to identify the beginning of left–right asymmetry in the heart
    From left to right: Claudio Badía Careaga, Jesús Vázquez, Enrique Calvo, Elías Herrero Galán, Natalia Vicente, Jorge Alegre Cebollada, Inés Martínez Martín, Carmen Suay Corredera, Diana Velázquez Carreras y Maria Rosaria Pricolo.
    Research
    27 Apr 2022
    Redox Biology: CNIC scientists discover a new mechanism involved in the modulation of heart muscle elasticity

    The results, published in Redox Biology, show the role of conserved cysteine residues in the elastic protein titin in the modulation of the mechanical properties of the myocardium
    Valentín Fuster
    About the CNIC
    4 Apr 2022
    Prestigious Award Named in Honor of Valentin Fuster, During American College of Cardiology Scientific Session

    CNIC leader will be recognized for his exceptional achievements at the 71st annual conference
    Research
    17 Mar 2022
    Circulation: A CNIC study highlights the risks of mitochondrial therapeutic interventions

    The mixing of mitochondrial DNAs (mtDNAs) of two distinct origins can have damaging medium- and long-term effects, according to the results of a new study published in Circulation
    . 3D model of a femoral artery obtained by real 3D imaging, revealing the location, number, and extent of distinct atherosclerotic plaques. In this sample, three plaques can be discerned (arrows), at the femoral bifurcation and distributed along the superficial branch.
    Research
    16 Mar 2022
    JACC: 3D matrix ultrasound accurately identifies cardiovascular injury in healthy individuals

    Scientists at the CNIC have led the development of a new three dimensional ultrasound method that improves the assessment of cardiovascular risk in healthy individuals