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E.g., 29/03/2026
E.g., 29/03/2026
Ana Simón Chica y David Filgueiras Rama
Research
10 Feb 2026

The study, published in Circulation Research, identifies cardiac fibroblasts and resident macrophages as essential contributors to the characteristic electrical activity that maintains this arrhythmia

Juan Pablo Ochoa, Pablo García-Pavía, Laura Lalaguna, Marina López-Olañeta, María Arévalo-Núñez de Arenas y Enrique Lara-Pezzi.
Research
9 Apr 2025

A CNIC team has developed an innovative gene therapy strategy for arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5), a rare and deadly inherited condition that particularly affects young men

Sandro Da Mesquita
Research
6 Jul 2024

Mayo Clinic College of Medicine and Science in Jacksonville

 

Marcos Siguero Álvarez, Luis Luna Zurita, José Luis de la Pompa y Brenda Giselle Flores Garza
Research
11 Dec 2023

The findings, published in the journal Circulation Research, not only highlight the gene regulatory mechanisms that control valve formation, but also offer clues for future medical advances


Cells use two mechanisms to detect force: one gradual and progressive mediated by newly identified large membrane depressions called dolines (left); the other abrupt, activated above a certain threshold, and mediated by minute membrane invaginations called caveolae (right).
Research
23 Dec 2022

A study published in Nature Cell Biology confirms that caveolae are essential for the mechanical responses of tissues subject to large mechanical forces (such as muscle, heart, blood vessels, and fat), whereas larger membrane depressions (termed 'dolines') are important for the response to weak or medium-strength forces

De izquierda a derecha: Enrique Lara-Pezzi, Laura Lalaguna, Laura Ramos, Elena González, María Villalba, Claudia Camarero, Marina López, Betel Olaizola, Ascensión Rey, Carlos Martí, Elísabet Bello y Javier Larrasa
Research
3 Sep 2021

The new findings, published in Circulation Research, could spur the development of new tools for the treatment of cardiac hypertrophy

Research
29 May 2020

The researcher Alejandro Sánchez Alvarado is one of the greatest experts in the study of the mechanisms involved, cellular and biological, in regeneration in the planaria model

De izda. a dcha.: Asier Echarri, Miguel Ángel del Pozo, Diana Velázquez, Carla Huerta, Sara Sánchez, María García, Raffaele Strippoli, Enrique Calvo, Jorge Alegre-Cebollada.
Research
20 Dec 2019

CNIC scientists have identified the molecular mechanisms that allow our cells to adapt to, protect themselves against, and survive mechanical stress

From left to right: Marta Román, Fernando Domínguez, Laura Padrón-Barthe, Pablo Garcia-Pavia, Giovanna Giovinazzo, Enrique Lara-Pezzi, Demetrio J. Santiago, Javier Larrasa-Alonso
Research
5 Sep 2019

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and Puerta de Hierro hospital in Majadahonda have found a possible treatment for this disease