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    E.g., 15/06/2025
    E.g., 15/06/2025
    SRSF3 expression in adult cardiomyocytes. Pink staining shows SRSF3 expression in cell nuclei, which are stained blue. Green staining shows the presence of troponin, a sarcomere protein expressed in cardiomyocytes.
    Research
    4 Jul 2019
    Circulation Research: CNIC scientists identify an essential protein for correct heart contraction and survival

    A new study published in Circulation Research shows that loss of cardiac expression of SRSF3 leads to a critical reduction in the expression of genes related to contraction
    Borja Ibáñez, Carlos Galán, Rodrigo Fernández, Eduardo Oliver, Gonzalo Pizarro, Manuel Lobo, Jean Paul Vilchez Tschischke, Antonio de Molina-Iracheta, Rocío Villena y Javier Sánchez-González
    Research
    19 Feb 2019
    JACC: Identified a very early marker of cardiac damage triggered by cancer treatment

    The results have implications for patient prognosis, since detection of this marker can prompt intervention to prevent irreversible damage
    De izda. a dcha.: José Antonio Enriquez, María del Mar Muñoz, Fátima Sánchez-Cabo, Luis Jesús Jiménez-Borreguero, Rocío Nieto-Arellano, Andrés González-Guerra, Carlos Torroja, José María Castellanos, y Concepción Jiménez.
    Research
    3 Apr 2018
    Science Translational Medicine: CNIC scientists identify a promising target for the treatment of heart failure

    The study is published in Science Translational Medicine and was conducted by researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC)
    Héctor Sánchez Iranzo, Andrés Sanz Morejón, María Galardi Castilla y Nadia Mercader Huber.
    Research
    8 Feb 2018
    Nature Communications: CNIC scientists describe a mechanism of heart regeneration in the zebrafish

    A new study published in Nature Communications describes a high level of plasticity among different cell populations in the regenerating zebrafish heart
    Jesús Vázquez, María Villalba, Sara Cogliati, Marina López, Paula Ortiz, José Antonio Enriquez, Laura Padrón, Elena Bonzón y Enrique Lara.
    Research
    6 Feb 2018
    JACC: An enzyme variant reduces cardiac hypertrophy and improves heart function

    The calcineurin variant CnAβ1 redirects glucose metabolism to increase production of antioxidant compounds, reducing cardiac hypertrophy and improving heart function

     
    Dra. Silvia Martín-Puig y Dr. Miguel Torres
    About the CNIC
    13 Dec 2017
    CNIC, first Spanish center to coordinate a project from the Leducq Foundation

    The project has been set up to examine how and why the capacity to develop new cardiac cells and repair the heart after an acute injury is lost with growth
    Gonzalo Pizarro, David Sanz-Rosa, Borja Ibáñez, Jaime García-Prieto, Mónica Gómez, Rocío Villena, and Andrés Hidalgo.
    Research
    18 Apr 2017
    'Nature Communications': CNIC scientists discover how a decades-old drug reduces the size of a heart attack

    The beta-blocker metoprolol can limit cardiac damage in patients having a heart attack
    Publications
    27 Aug 2015
    European Heart Journal: Investigadores españoles descubren que la amiloidosis senil es la causa del 7% al 10% de los casos de insuficiencia cardiaca en los mayores de 60 años

    Investigadores del CNIC y del H Puerta de Hierro Majadahonda han publicado un trabajo en la revista European Heart Journal en el que han analizado 120 pacientes mayores de 60 años ingresados por descompensación de insuficiencia cardiaca
    Publications
    31 Mar 2014
    Investigadores del CNIC confirman que la función cardiaca de pacientes con infarto mantiene la mejora seis meses después de recibir un fármaco de menos de dos euros
    Publications
    4 Oct 2013
    Logran reducir el daño cardiaco durante un infarto con un fármaco de menos de dos euros