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E.g., 12/11/2024
E.g., 12/11/2024
Cardiovascular risk factors (particularly metabolic syndrome, insulin resistance, and diabetes) alter coronary microvascular function and increase the risk of atherosclerotic disease, which itself leads to changes in the coronary microcirculation.
Research
19 Sep 2024

A study from CNIC reveals how risk factors and subclinical atherosclerosis affect heart microcirculation in asymptomatic middle-aged individuals. The research, published in JACC: Cardiovascular Imaging, highlights the importance of assessing the heart vessels' ability to regulate blood flow and predict future cardiovascular risk

Figure
Research
13 Sep 2024

RESILIENCE is a clinical trial funded by the European Commission (H2020 Programme) that aims to reduce the prevalence of heart failure in cancer survivors

CNIC researchers
Research
30 Aug 2024

Two studies carried out at the CNIC provide key information about a newly identified cardiovascular risk factor, clonal hematopoiesis, and its treatment with the ancient medication colchicine

Dr. Fuster recibe el premio
Agustín Clemente-Moragón, Borja Ibáñez, Anabel Díaz-Guerra, Laura Cádiz, Carlos Galán-Arriola, Miguel Fernández-Tocino, Mónica Gómez, Rocío Villena-Gutiérrez, y Eduardo Oliver.
Research
16 Apr 2024

The study, published in the journal JACC: CardioOncology, identifies mitochondrial function and heart metabolism as targets for possible treatments to protect against anthracycline-induced cardiotoxicity

Ayelén M. Santamans y Guadalupe Sabio
Research
19 Jan 2024

A team led by scientists from the CNIC and CNIO has identified a potential therapeutic target that protects the heart in patients with pulmonary hypertension

Edward Pearce
Research
21 Dec 2023

Johns Hopkins UniversityBloomberg School of Public HealthBaltimore

Marcos Siguero Álvarez, Luis Luna Zurita, José Luis de la Pompa y Brenda Giselle Flores Garza
Research
11 Dec 2023

The findings, published in the journal Circulation Research, not only highlight the gene regulatory mechanisms that control valve formation, but also offer clues for future medical advances


Neuregulin-1 induces changes in actin filaments during ventricular maturation. Actinin staining of a mouse embryo heart reveals a striated actin pattern corresponding to mature trabecular sarcomeres (green). The magnified view shows the differences in luminosity that distinguish the more organized actin filaments of the trabecular myocardium from the less organized compact layer
Research
10 Nov 2023

Neuregulin-1 (Nrg1) plays an essential role in the transformation of the heart from its delicate primordial structure into the powerful beating mature organ