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E.g., 07/02/2023
E.g., 07/02/2023
Transverse heart sections from wild type mice (WT) and transgenic mice overexpressing beta-3 adrenergic receptor in cardiomyocytes (c-h3tg) after 3 months of aortic stenosis (transaortic constriction, TAC) or control (sham). Hypertrophy after TAC was less severe in the transgenic mice
Research
29 Nov 2022

The experimental study, led by researchers at the CNIC, shows that boosting the expression of this adrenalin receptor in heart cells improves mitochondrial function in the heart

Descubren un factor clave que protege el corazón tras un infarto
About the CNIC
2 Nov 2022

A new study defines a mechanism that regulates inflammation after a myocardial infarction, opening a path to the use of the receptor

Fernando de Frutos y el Dr. Pablo García Pavía.
Research
29 Aug 2022

The findings, published in the Journal of the American College of Cardiology (JACC), represent a first step towards the personalized treatment of patients with this disease

Valentín Fuster
Research
26 Aug 2022

The results of the SECURE trial, coordinated by CNIC were presented in a Hot Line session at the European Society of Cardiology meeting (ESC 2022) in Barcelona and published at the NEJM

Miguel Palomino Segura, Georgiana Crainiciuc, Jon Sicilia y Andrés Hidalgo
Research
5 Jan 2022

Scientists at the CNIC have developed a simple model for studying the behavior of immune cells in live animals and have identified a harmful cell behavior pattern associated with cardiovascular disease


Representative transmurality map from an 3D-upsampled model with a short axis view at high-magnification to illustrate the 3D methodology for transmural-based scar assessment from images obtained with conventional 2D delayed gadolinium-enhanced CMR
Research
28 Sep 2021

This innovative technology may provide an efficient approach in clinical practice after manual or automatic segmentation of myocardial borders in a small number of conventional 2D slices and automatic scar detection


About the CNIC
6 Aug 2021

CNIC and the Mario Negri Institute in Milan (Italy) coordinate REBOOT, a project that aims to study whether treatment with beta-blockers is beneficial for patients who have suffered a myocardial infarction

First biomarker in blood that distinguishes myocarditis from an acute myocardial infarction
Research
27 May 2021

The diagnosis of acute myocarditis is challenging, and the availability of a sensitive and specific early marker of acute myocardial inflammation could have a major impact on its clinical diagnosis


A 3-dimensional magnetic resonance image form a patient who has undergone an acute myocardial infarction. The heart is visible in the center of the image. Healthy (non-infarcted) cardiac muscle is indicated by asterisks, whereas arrows point to the infarcted region. MRI can reveal the extent of the area affected by inflammation after a heart attack (the yellow infarcted region marked by arrows). Serial MRI studies reveal thta this inflammatory reaction appears immediately after the infarction but then rapid
Research
22 Aug 2017

The study overturns the dogma that infarction is followed by progressive repair of the injured myocardium.

About the CNIC
1 Jun 2017

Dr. Ibáñez, Director of Clinical Research at the CNIC, has received an award for his contribution to the fight against cardiovascular diseases