Selected publications

Nieto-Marín P, Tinaquero D, Utrilla RG, Cebrián J, González-Guerra A, Crespo-García T, Cámara-Checa A, Rubio-Alarcón M, Dago M, Alfayate S, Filgueiras D, Peinado R, López-Sendón JL, Jalife J, Tamargo J, Bernal JA, Caballero R, Delpón E Tbx5 variants disrupt Nav1.5 function differently in patients diagnosed with Brugada or Long QT Syndrome Cardiovasc Res (2021) :cvab045
Quintanilla JG, Shpun S, Jalife J, Filgueiras-Rama D Novel approaches to mechanism-based atrial fibrillation ablation Cardiovasc Res (2021) 117:1662-1681
Macías Á, Díaz-Larrosa JJ, Blanco Y, Fanjul V, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, da Rocha AM, Ponce-Balbuena D, Allan A, Filgueiras-Rama D, Jalife J, Andrés V Paclitaxel mitigates structural alterations and cardiac conduction system defects in a mouse model of Hutchinson-Gilford progeria syndrome Cardiovasc Res (2021) :cvab055
Merino-Caviedes S, Gutierrez LK, Alfonso-Almazán JM, Sanz-Estébanez S, Cordero-Grande L, Quintanilla JG, Sánchez-González J, Marina-Breysse M, Galán-Arriola C, Enríquez-Vázquez D, Torres C, Pizarro G, Ibáñez B, Peinado R, Merino JL, Pérez-Villacastín J, Jalife J, López-Yunta M, Vázquez M, Aguado-Sierra J, González-Ferrer JJ, Pérez-Castellano N, Martín-Fernández M, Alberola-López C, Filgueiras-Rama D Time-efficient three-dimensional transmural scar assessment provides relevant substrate characterization for ventricular tachycardia features and long-term recurrences in ischemic cardiomyopathy Sci Rep (2021) 11:18722
la Rosa G, Quintanilla JG, Salgado R, Gonzalez-Ferrer JJ, Canadas-Godoy V, Perez-Villacastin J, Jalife J, Perez-Castellano N, Filgueiras-Rama D Anatomical targets and expected outcomes of catheter-based ablation of atrial fibrillation in 2020 Pacing Clin Electrophysiol (2021) 44:341-59
Repisalud
Alvarez-Franco A, Rouco R, Ramirez RJ, Guerrero-Serna G, Tiana M, Cogliati S, Kaur K, Saeed M, Magni R, Enriquez JA, Sanchez-Cabo F, Jalife J, Manzanares M Transcriptome and proteome mapping in the sheep atria reveal molecular features of atrial fibrillation progression Cardiovasc Res (2020) Nov 2 [Epub ahead of print]
Filgueiras-Rama D, Vasilijevic J, Jalife J, Noujaim SN, Alfonso JM, Nicolas-Avila JA, Gutierrez C, Zamarreno N, Hidalgo A, Bernabe A, Cop CP, Ponce-Balbuena D, Guerrero-Serna G, Calle D, Desco M, Ruiz-Cabello J, Nieto A, Falcon A Human Influenza A virus causes myocardial and cardiac-specific conduction system infection associated with early inflammation and premature death Cardiovasc Res (2020) May 4 [Epub ahead of print]
Lillo-Castellano JM, Gonzalez-Ferrer JJ, Marina-Breysse M, Martinez-Ferrer JB, Perez-Alvarez L, Alzueta J, Martinez JG, Rodriguez A, Rodriguez-Perez JC, Anguera I, Vinolas X, Garcia-Alberola A, Quintanilla JG, Alfonso-Almazan JM, Garcia J, Borrego L, Canadas-Godoy V, Perez-Castellano N, Perez-Villacastin J, Jimenez-Diaz J, Jalife J, Filgueiras-Rama D Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices Europace (2020) 22:704-15
Link to the full text in Repisalud
Park SS, Ponce-Balbuena D, Kuick R, Guerrero-Serna G, Yoon J, Mellacheruvu D, Conlon KP, Basrur V, Nesvizhskii AI, Jalife J, Rual JF Kir2.1 Interactome Mapping Uncovers PKP4 as a Modulator of the Kir2.1-Regulated Inward Rectifier Potassium Currents Mol Cell Proteomics (2020) 19:1436-1449
Tinaquero D, Crespo-Garcia T, Utrilla RG, Nieto-Marin P, Gonzalez-Guerra A, Rubio-Alarcon M, Camara-Checa A, Dago M, Matamoros M, Perez-Hernandez M, Tamargo M, Cebrian J, Jalife J, Tamargo J, Bernal JA, Caballero R, Delpon E, ITACA Investigators The p.P888L SAP97 polymorphism increases the transient outward current (Ito,f) and abbreviates the action potential duration and the QT interval Sci Rep (2020) 10:10707
Link to the full text in Repisalud
Jalife J. The tornadoes of sudden cardiac arrest. Nature (2018) 555:597-98
Calvo D, Filgueiras-Rama D, Jalife J. Mechanisms and Drug Development in Atrial Fibrillation. Pharmacol Rev (2018) 70:505-25
Ponce-Balbuena D, Guerrero-Serna G, Valdivia CR, Caballero R, Diez-Guerra FJ, Jimenez-Vazquez EN, Ramirez RJ, Monteiro da Rocha A, Herron TJ, Campbell KF, Willis BC, Alvarado FJ, Zarzoso M, Kaur K, Perez-Hernandez M, Matamoros M, Valdivia HH, Delpon E, Jalife J. Cardiac Kir2.1 and NaV1.5 Channels Traffic Together to the Sarcolemma to Control Excitability. Circ Res (2018) 122:1501-16
Takemoto Y, Ramirez RJ, Kaur K, Salvador-Montañés O, Ponce-Balbuena D, Ramos-Mondragón R, Ennis SR, Guerrero-Serna G, Berenfeld O, Jalife J. Eplerenone Reduces Atrial Fibrillation Burden Without Preventing Atrial Electrical Remodeling. J Am Coll Cardiol (2017) 70:2893-905
Willis BC, Pandit S, Ponce-Balbuena D, Zarzoso M, Guerrero-Serna G, Limbu B, Deo M, Cammors E, Ramirez RJ, Mironov S, Herron TJ, Valdivia HH, Jalife J. Constitutive Intracellular Na+ Excess in Purkinje Cells Promotes Arrhythmogenesis at Lower Levels of Stress than Ventricular Myocytes from Mice with Catecholaminergic Polymorphic Ventricular Tachycardia. Circulation (2016) 133:2348-59
Link to the full text in Repisalud
Takemoto Y, Ramirez RJ, Yokokawa M, Kaur K, Ponce-Balbuena D, Sinno MC, Willis BC, Ghanbari H, Ennis SR, Guerrero-Serna G, Henzi BC, Latchamsetty R, Ramos-Mondragon R, Musa H, Martins RP, Pandit SV, Noujaim SF, Crawford T, Jongnarangsin K, Pelosi F, Bogun F, Chugh A, Berenfeld O, Morady F, Oral H, Jalife J. Galectin-3 Regulates Atrial Fibrillation Remodeling and Predicts Catheter Ablation Outcomes JACC Basic Transl Sci (2016) 1:143-54
Martins RP, Kaur K, Hwang E, Ramirez RJ, Willis BC, Filgueiras-Rama D, Ennis SR, Takemoto Y, Ponce-Balbuena D, Zarzoso M, O'Connell RP, Musa H, Guerrero-Serna G, Avula UM, Swartz MF, Bhushal S, Deo M, Pandit SV, Berenfeld O, Jalife J. Dominant Frequency Increase Rate Predicts Transition from Paroxysmal to Long-Term Persistent Atrial Fibrillation. Circulation (2014) 129:1472-82
Pandit SV, Jalife J. Rotors and the dynamics of cardiac fibrillation. Circ Res (2013) 112:849-62
Herron TJ, Lee P, Jalife J. Optical imaging of voltage and calcium in cardiac cells & tissues. Circ Res (2012) 110:609-23
Milstein ML, Musa H, Balbuena DP, Anumonwo JM, Auerbach DS, Furspan PB, Hou L, Hu B, Schumacher SM, Vaidyanathan R, Martens JR, Jalife J. Dynamic reciprocity of sodium and potassium channel expression in a macromolecular complex controls cardiac excitability and arrhythmia. Proc Natl Acad Sci U S A (2012) 109:2134-43