Selected publications

Filgueiras-Rama D, Vasilijevic J, Jalife J, Noujaim SN, Alfonso JM, Nicolas-Avila JA, Gutierrez C, Zamarreno N, Hidalgo A, Bernabe A, Cop CP, Ponce-Balbuena D, Guerrero-Serna G, Calle D, Desco M, Ruiz-Cabello J, Nieto A, Falcon A Human Influenza A virus causes myocardial and cardiac-specific conduction system infection associated with early inflammation and premature death Cardiovasc Res (2020) May 4 [Epub ahead of print]
Lillo-Castellano JM, Gonzalez-Ferrer JJ, Marina-Breysse M, Martinez-Ferrer JB, Perez-Alvarez L, Alzueta J, Martinez JG, Rodriguez A, Rodriguez-Perez JC, Anguera I, Vinolas X, Garcia-Alberola A, Quintanilla JG, Alfonso-Almazan JM, Garcia J, Borrego L, Canadas-Godoy V, Perez-Castellano N, Perez-Villacastin J, Jimenez-Diaz J, Jalife J, Filgueiras-Rama D Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices Europace (2020) 22:704-15
Link to the full text in Repisalud
Quintanilla JG, Alfonso-Almazan JM, Perez-Castellano N, Pandit SV, Jalife J, Perez-Villacastin J, Filgueiras-Rama D Instantaneous Amplitude and Frequency Modulations Detect The Footprint of Rotational Activity and Reveal Stable Driver Regions as Targets for Persistent Atrial Fibrillation Ablation Circ Res (2019) 125:609-27
Link to the full text in Repisalud
Lee P, Quintanilla JG, Alfonso-Almazan JM, Galan-Arriola C, Yan P, Sanchez-Gonzalez J, Perez-Castellano N, Perez-Villacastin J, Ibanez B, Loew LM, Filgueiras-Rama D. In-Vivo Ratiometric Optical Mapping Enables High-Resolution Cardiac Electrophysiology in Pig Models. Cardiovasc Res (2019) 115:1659-71
Link to the full text in Repisalud
Lopez-Yunta M, Leon DG, Alfonso-Almazan JM, Marina-Breysse M, Quintanilla JG, Sanchez-Gonzalez J, Galan-Arriola C, Canadas-Godoy V, Enriquez-Vazquez D, Torres C, Ibanez B, Perez-Villacastin J, Perez-Castellano N, Jalife J, Vazquez M, Aguado-Sierra J, Filgueiras-Rama D. Implications of bipolar voltage mapping and magnetic resonance imaging resolution in biventricular scar characterization after myocardial infarction. Europace (2019) 21:163-174
Link to the full text in Repisalud
Leon DG, Lopez-Yunta M, Alfonso-Almazan JM, Marina-Breysse M, Quintanilla JG, Sanchez-Gonzalez J, Galan-Arriola C, Castro-Nunez F, Gonzalez-Ferrer JJ, Ibanez B, Perez-Villacastin J, Perez-Castellano N, Fuster V, Jalife J, Vazquez M, Aguado-Sierra J, Filgueiras-Rama D. Three-dimensional cardiac fibre disorganization as a novel parameter for ventricular arrhythmia stratification after myocardial infarction. Europace (2019) 21:822-32
Link to the full text in Repisalud
Dorado B, Ploen GG, Barettino A, Macias A, Gonzalo P, Andres-Manzano MJ, Gonzalez-Gomez C, Galan-Arriola C, Alfonso JM, Lobo M, Lopez-Martin GJ, Molina A, Sanchez-Sanchez R, Gadea J, Sanchez-Gonzalez J, Liu Y, Callesen H, Filgueiras-Rama D, Ibanez B, Sorensen CB, Andres V Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome Cell Discov (2019) 5:16
Link to the full text in Repisalud
Alfonso-Almazan JM, Quintanilla JG, Garcia-Torrent MJ, Laguna-Castro S, Rodriguez-Bobada C, Gonzalez P, Gonzalez-Ferrer JJ, Salinas P, Canadas-Godoy V, Moreno J, Borrego-Bernabe L, Perez-Castellano N, Jalife J, Perez-Villacastin J, Filgueiras-Rama D Lesion Index Titration Using Contact-Force Technology Enables Safe and Effective Radiofrequency Lesion Creation at the Root of the Aorta and Pulmonary Artery Circ Arrhythm Electrophysiol (2019) 12:e007080
Link to the full text in Repisalud
Ramirez RJ, Takemoto Y, Martins RP, Filgueiras-Rama D, Ennis SR, Mironov S, Bhushal S, Deo M, Rajamani S, Berenfeld O, Belardinelli L, Jalife J, Pandit SV Mechanisms by Which Ranolazine Terminates Paroxysmal but Not Persistent Atrial Fibrillation Circ Arrhythm Electrophysiol (2019) 12:e005557
Link to the full text in Repisalud
Calvo D, Filgueiras-Rama D, Jalife J. Mechanisms and Drug Development in Atrial Fibrillation. Pharmacol Rev (2018) 70:505-25
Caballero R, Utrilla RG, Amoros I, Matamoros M, Perez-Hernandez M, Tinaquero D, Alfayate S, Nieto-Marin P, Guerrero-Serna G, Liu QH, Ramos-Mondragon R, Ponce-Balbuena D, Herron T, Campbell KF, Filgueiras-Rama D, Peinado R, Lopez-Sendon JL, Jalife J, Delpon E, Tamargo J. Tbx20 controls the expression of the KCNH2 gene and of hERG channels. Proc Natl Acad Sci U S A (2017) 114:E416-25
Mirelis JG, Sanchez-Gonzalez J, Zorio E, Ripoll-Vera T, Salguero-Bodes R, Filgueiras-Rama D, Gonzalez-Lopez E, Gallego-Delgado M, Fernandez-Jimenez R, Soleto MJ, Nunez J, Pizarro G, Sanz J, Fuster V, Garcia-Pavia P, Ibanez B. Myocardial Extracellular Volume Is not Associated With Malignant Ventricular Arrhythmias in High-risk Hypertrophic Cardiomyopathy. Rev Esp Cardiol (2017) 70:933-40
Lee P, Calvo CJ*, Alfonso-Almazan JM, Quintanilla JG, Chorro FJ, Yan P, Loew LM, Filgueiras-Rama D*, Millet J (PL and CJC contributed equally; DFR is the corresponding author) Low-Cost Optical Mapping Systems for Panoramic Imaging of Complex Arrhythmias and Drug-Action in Translational Heart Models. Sci Rep (2017) 7:43217
Link to the full text in Repisalud
Rivera-Torres J, Calvo CJ, Llach A, Guzman-Martinez G, Caballero R, Gonzalez-Gomez C, Jimenez-Borreguero LJ, Guadix JA, Osorio FG, Lopez-Otin C, Herraiz-Martinez A, Cabello N, Vallmitjana A, Benitez R, Gordon LB, Jalife J, Perez-Pomares JM, Tamargo J, Delpon E, Hove-Madsen L, Filgueiras-Rama D, Andres V. Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations. Proc Natl Acad Sci U S A (2016) 113:E7250–9
Link to the full text in Repisalud
Lillo-Castellano JM, Marina-Breysse M, Gomez-Gallanti A, Martinez-Ferrer JB, Alzueta J, Perez-Alvarez L, Alberola A, Fernandez-Lozano I, Rodriguez A, Porro R, Anguera I, Fontenla A, Gonzalez-Ferrer JJ, Canadas-Godoy V, Perez-Castellano N, Garofalo D, Salvador-Montanes O, Calvo CJ, Quintanilla JG, Peinado R, Mora-Jimenez I, Perez-Villacastin J, Rojo-Alvarez JL, Filgueiras-Rama D. Safety threshold of R-wave amplitudes in patients with implantable cardioverter defibrillator. Heart (2016) 102:1662-70
Quintanilla JG, Perez-Villacastin J, Perez-Castellano N, Pandit SV, Berenfeld O, Jalife J, Filgueiras-Rama D. Mechanistic Approaches to Detect, Target, and Ablate the Drivers of Atrial Fibrillation. Circ Arrhythm Electrophysiol (2016) 9:e002481
Filgueiras-Rama D, Calvo CJ, Salvador-Montanes O, Cadenas R, Ruiz-Cantador J, Armada E, Rey JR, Merino JL, Peinado R, Perez-Castellano N, Perez-Villacastin J, Quintanilla JG, Jimenez S, Castells F, Chorro FJ, Lopez-Sendon JL, Berenfeld O, Jalife J, de Sa EL, Millet J Spectral analysis-based risk score enables early prediction of mortality and cerebral performance in patients undergoing therapeutic hypothermia for ventricular fibrillation and comatose status Int J Cardiol (2015) 186:250-8
Martins RP, Kaur K, Hwang E, Ramirez RJ, Willis BC, Filgueiras-Rama D, Ennis SR, Takemoto Y, Ponce-Balbuena D, Zarzoso M, O'Connell RP, Musa H, Guerrero-Serna G, Avula UM, Swartz MF, Bhushal S, Deo M, Pandit SV, Berenfeld O, Jalife J. Dominant Frequency Increase Rate Predicts Transition from Paroxysmal to Long-Term Persistent Atrial Fibrillation. Circulation (2014) 129:1472-82