Selected publications

Caballero R, Utrilla RG, Amoros I, Matamoros M, Perez-Hernandez M, Tinaquero D, Alfayate S, Nieto-Marin P, Guerrero-Serna G, Liu QH, Ramos-Mondragon R, Ponce-Balbuena D, Herron T, Campbell KF, Filgueiras-Rama D, Peinado R, Lopez-Sendon JL, Jalife J, Delpon E, Tamargo J. Tbx20 controls the expression of the KCNH2 gene and of hERG channels. Proc Natl Acad Sci U S A (2017) 114:E416-25
Lee P, Calvo CJ*, Alfonso-Almazan JM, Quintanilla JG, Chorro FJ, Yan P, Loew LM, Filgueiras-Rama D*, Millet J (PL and CJC contributed equally; DFR is the corresponding author) Low-Cost Optical Mapping Systems for Panoramic Imaging of Complex Arrhythmias and Drug-Action in Translational Heart Models. Sci Rep (2017) 7:43217
Rivera-Torres J, Calvo CJ, Llach A, Guzman-Martinez G, Caballero R, Gonzalez-Gomez C, Jimenez-Borreguero LJ, Guadix JA, Osorio FG, Lopez-Otin C, Herraiz-Martinez A, Cabello N, Vallmitjana A, Benitez R, Gordon LB, Jalife J, Perez-Pomares JM, Tamargo J, Delpon E, Hove-Madsen L, Filgueiras-Rama D, Andres V. Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations. Proc Natl Acad Sci U S A (2016) 113:E7250–9
Lillo-Castellano JM, Marina-Breysse M, Gomez-Gallanti A, Martinez-Ferrer JB, Alzueta J, Perez-Alvarez L, Alberola A, Fernandez-Lozano I, Rodriguez A, Porro R, Anguera I, Fontenla A, Gonzalez-Ferrer JJ, Canadas-Godoy V, Perez-Castellano N, Garofalo D, Salvador-Montanes O, Calvo CJ, Quintanilla JG, Peinado R, Mora-Jimenez I, Perez-Villacastin J, Rojo-Alvarez JL, Filgueiras-Rama D. Safety threshold of R-wave amplitudes in patients with implantable cardioverter defibrillator. Heart (2016) 102:1662-70
Quintanilla JG, Perez-Villacastin J, Perez-Castellano N, Pandit SV, Berenfeld O, Jalife J, Filgueiras-Rama D. Mechanistic Approaches to Detect, Target, and Ablate the Drivers of Atrial Fibrillation. Circ Arrhythm Electrophysiol (2016) 9:e002481
Filgueiras-Rama D, Calvo CJ, Salvador-Montanes O, Cadenas R, Ruiz-Cantador J, Armada E, Rey JR, Merino JL, Peinado R, Perez-Castellano N, Perez-Villacastin J, Quintanilla JG, Jimenez S, Castells F, Chorro FJ, Lopez-Sendon JL, Berenfeld O, Jalife J, de Sa EL, Millet J Spectral analysis-based risk score enables early prediction of mortality and cerebral performance in patients undergoing therapeutic hypothermia for ventricular fibrillation and comatose status Int J Cardiol (2015) 186:250-8
Quintanilla JG, Moreno J, Archondo T, Usandizaga E, Molina-Morua R, Rodriguez-Bobada C, Gonzalez P, Garcia-Torrent MJ, Filgueiras-Rama D, Perez-Castellano N, Macaya C, Perez-Villacastin J Increased intraventricular pressures are as harmful as the electrophysiological substrate of heart failure in favoring sustained reentry in the swine heart. Heart Rhythm (2015) 12:2172-83
Martins RP, Kaur K, Hwang E, Ramirez RJ, Willis BC, Filgueiras-Rama D, Ennis SR, Takemoto Y, Ponce-Balbuena D, Zarzoso M, O'Connell RP, Musa H, Guerrero-Serna G, Avula UM, Swartz MF, Bhushal S, Deo M, Pandit SV, Berenfeld O, Jalife J. Dominant Frequency Increase Rate Predicts Transition from Paroxysmal to Long-Term Persistent Atrial Fibrillation. Circulation (2014) 129:1472-82
Berenfeld O, Yamazaki M, Filgueiras-Rama D, Kalifa J. Surface and intramural reentrant patterns during atrial fibrillation in the sheep. Methods Inf Med (2014) 53:314-9
Filgueiras-Rama D, Martins RP, Mironov S, Yamazaki M, Calvo CJ, Ennis SR, Bandaru K, Noujaim SF, Kalifa J, Berenfeld O, Jalife J Chloroquine terminates stretch-induced atrial fibrillation more effectively than flecainide in the sheep heart Circ Arrhythm Electrophysiol (2012) 5:561-70
Filgueiras-Rama D, Price NF, Martins RP, Yamazaki M, Avula UM, Kaur K, Kalifa J, Ennis SR, Hwang E, Devabhaktuni V, Jalife J, Berenfeld O Long-term frequency gradients during persistent atrial fibrillation in sheep are associated with stable sources in the left atrium. Circ Arrhythm Electrophysiol (2012) 5:1160-7
Pandit SV, Zlochiver S, Filgueiras-Rama D, Mironov S, Yamazaki M, Ennis SR, Noujaim SF, Workman AJ, Berenfeld O, Kalifa J, Jalife J. Targeting atrioventricular differences in ion channel properties for terminating acute atrial fibrillation in pigs Cardiovasc Res (2011) 89:843-51