Transverse heart sections from wild type mice (WT) and transgenic mice overexpressing beta-3 adrenergic receptor in cardiomyocytes (c-h3tg) after 3 months of aortic stenosis (transaortic constriction, TAC) or control (sham). Hypertrophy after TAC was less severe in the transgenic mice
    Research, Publications
    Basic Research in Cardiology: A new therapeutic target for the prevention of heart failure due to aortic stenosis

    The experimental study, led by researchers at the CNIC, shows that boosting the expression of this adrenalin receptor in heart cells improves mitochondrial function in the heart

    Imagen obtenida por microscopía confocal en la que se observa el borde de la cicatriz glial producida tras el infarto cerebral, lo cual dificulta la posterior regeneración de la zona. Este evento es atenuado en gran medida a través del tratamiento con metoprolol intravenoso pre-reperfusión.
    Research, Publications
    BJP: CNIC scientists identify a neuroprotective action of metoprolol after a stroke

    Metoprolol, an established drug in the cardiologists armory, protects the brain during a stroke and greatly reduces its consequences


    Bone marrow contributes to the development of atherosclerosis
    Research, Publications
    EHJ: Bone marrow contributes to the development of atherosclerosis

    The new discovery suggests new research avenues toward the discovery of interventions to prevent or arrest atherosclerosis

    . 3D model of a femoral artery obtained by real 3D imaging, revealing the location, number, and extent of distinct atherosclerotic plaques. In this sample, three plaques can be discerned (arrows), at the femoral bifurcation and distributed along the superficial branch.
    Research, Publications
    JACC: 3D matrix ultrasound accurately identifies cardiovascular injury in healthy individuals

    Scientists at the CNIC have led the development of a new three dimensional ultrasound method that improves the assessment of cardiovascular risk in healthy individuals


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