Selected publications

Fuster JJ, Zuriaga MA, Zorita V, MacLauchlan S, Polackal MN, Viana-Huete V, Ferrer-Perez A, Matesanz N, Herrero-Cervera A, Sano S, Cooper MA, Gonzalez-Navarro H, Walsh K TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity Cell Rep (2020) 33:108326
Link to the full text in Repisalud
Wang Y, Sano S, Yura Y, Ke Z, Sano M, Oshima K, Ogawa H, Horitani K, Min KD, Miura-Yura E, Kour A, Evans MA, Zuriaga MA, Hirschi KK, Fuster JJ, Pietras EM, Walsh K Tet2-mediated clonal hematopoiesis in non-conditioned mice accelerates age-associated cardiac dysfunction JCI Insight (2020) 5:135204
Sano S, Oshima K, Wang Y, MacLauchlan S, Katanasaka Y, Sano M, Zuriaga MA, Yoshiyama M, Goukassian D, Cooper MA, Fuster JJ, Walsh K Tet2-mediated clonal hematopoiesis accelerates experimental heart failure through an IL-1β/NLRP3 inflammasome mechanism J Am Coll Cardiol (2018) 72:875-86
Fuster JJ* and Walsh K* (JJF and KW are co-correspondig authors) Somatic mutations and clonal hematopoiesis: unexpected potential new drivers of age-related cardiovascular disease Circ Res (2018) 122:523-32
Fuster JJ*, MacLauchlan S, Zuriaga MA, Polackal MN, Ostriker AC, Chakraborty R, Wu C-L, Sano S, Muralidharan S, Rius C, Vuong J, Jacob S, Muralidhar V, Robertson AAB, Cooper MA, Andres V, Hirschi KK, Martin KA, Walsh K* (JJF and KW are co-corresponding authors). Clonal hematopoiesis associated with Tet2 deficiency accelerates atherosclerosis development in mice. Science (2017) 355:842-7
Link to the full text in Repisalud
Fuster JJ*, Ouchi N, Gokce N, Walsh K* (JJF and KW are co-corresponding authors) Obesity-Induced Changes in Adipose Tissue Microenvironment and Their Impact on Cardiovascular Disease Circ Res (2016) 118:1786-807
Fuster JJ, Zuriaga MA, Ngo DT, Farb MG, Aprahamian T, Yamaguchi TP, Gokce N, Walsh K Non-canonical Wnt signaling promotes obesity-induced adipose tissue inflammation and metabolic dysfunction Diabetes (2015) 64:1235-48
Kikuchi R, Nakamura K, MacLauchlan S, Ngo DT, Shimizu I, Fuster JJ, Katanasaka Y, Yoshida S, Qiu Y, Yamaguchi TP, Matsushita T, Murohara T, Gokce N, Bates DO, Hamburg NM, Walsh K An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease Nat Med (2014) 20:1464-71