Selected publications

    Siguero-Álvarez M, Salguero-Jiménez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sánchez-Sáez F, Piñeiro-Sabarís R, Felipe-Medina N, Torroja C, José Gómez M, Sabater-Molina M, Escribá R, Richaud-Patin I, Iglesias-García O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibañez B, Monserrat L, María Pérez-Pomares J, Sánchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL. A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation (2023) 147:47-65
    Link to the full text in Repisalud
    Domínguez F, Lalaguna L, Martínez-Martín I, Piqueras-Flores J, Rasmussen TB, Zorio E, Giovinazzo G, Prados B, Ochoa JP, Bornstein B, González-López E, Velázquez-Carreras D, Pricolo MR, Gutiérrez-Agüera F, Bernal JA, Herrero-Galán E, Alegre-Cebollada J, Lara-Pezzi E, García-Pavía P. Titin Missense Variants as a Cause of Familial Dilated Cardiomyopathy. Circulation (2023) 147:1711-1713
    Link to the full text in Repisalud
    Grego-Bessa J, Gómez-Apiñaniz P, Prados B, Gómez MJ, MacGrogan D, de la Pompa JL. Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development Circ Res (2023) 133:927-943
    Pun-García A, Clemente-Moragón A, Villena-Gutierrez R, Gómez M, Sanz-Rosa D, Díaz-Guerra A, Prados B, Medina JP, Montó F, Ivorra MD, Márquez-López C, Cannavo A, Bernal JA, Koch WJ, Fuster V, de la Pompa JL, Oliver E, Ibanez B. Beta-3 adrenergic receptor overexpression reverses aortic stenosis-induced heart failure and restores balanced mitochondrial dynamics. Basic Res Cardiol (2022) 117:62
    Link to the full text in Repisalud
    Tiana M, Lopez-Jimenez E, de Aja JS, Barral A, Victorino J, Badia-Careaga C, Rollan I, Rouco R, Santos E, Sanchez-Iranzo H, Acemel RD, Torroja C, Adan J, Andres-Leon E, Gomez-Skarmeta JL, Giovinazzo G, Sanchez-Cabo F, Manzanares M. Pluripotency factors regulate the onset of Hox cluster activation in the early embryo. Sci Adv (2022) 8
    Link to the full text in Repisalud
    Delgado I, Giovinazzo G, Temiño S, Gauthier Y, Balsalobre A, Drouin J, Torres M Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors Nat Commun (2021) 12:3086
    Link to the full text in Repisalud
    Prados B, Del Toro R, MacGrogan D, Gómez-Apiñániz P, Papoutsi T, Muñoz-Cánoves P, Méndez-Ferrer S, de la Pompa JL Heterotopic ossification in mice overexpressing Bmp2 in Tie2+ lineages Cell Death Dis (2021) 12:729
    Durán Alonso MB, Vendrell V, López-Hernández I, Alonso MT, Martin DM, Giráldez F, Carramolino L, Giovinazzo G, Vázquez E, Torres M, Schimmang T Meis2 Is Required for Inner Ear Formation and Proper Morphogenesis of the Cochlea Front Cell Dev Biol (2021) 9:679325
    Delgado I, López-Delgado AC, Roselló-Díez A, Giovinazzo G, Cadenas V, Fernández-de-Manuel L, Sánchez-Cabo F, Anderson MJ, Lewandoski M, Torres M Proximo-distal positional information encoded by an Fgf-regulated gradient of homeodomain transcription factors in the vertebrate limb Sci Adv (2020) 6:eaaz0742
    Link to the full text in Repisalud
    Padron-Barthe L, Villalba-Orero M, Gomez-Salinero JM, Dominguez F, Roman M, Larrasa-Alonso J, Ortiz-Sanchez P, Martinez F, Lopez-Olaneta M, Bonzon-Kulichenko E, Vazquez J, Marti-Gomez C, Santiago DJ, Prados B, Giovinazzo G, Gomez-Gaviro MV, Priori S, Garcia-Pavia P, Lara-Pezzi E Severe Cardiac Dysfunction and Death Caused by Arrhythmogenic Right Ventricular Cardiomyopathy Type 5 Are Improved by Inhibition of Glycogen Synthase Kinase-3beta Circulation (2019) 140:1188-1204
    Link to the full text in Repisalud
    Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade eLife (2019) 8:e49977
    Link to the full text in Repisalud
    Prados B, Gomez-Apinaniz P, Papoutsi T, Luxan G, Zaffran S, Perez-Pomares JM, de la Pompa JL. Myocardial Bmp2 gain causes ectopic EMT and promotes cardiomyocyte proliferation and immaturity. Cell Death Dis (2018) 9:399
    Link to the full text in Repisalud
    Papoutsi T, Luna-Zurita L, Prados B, Zaffran S, de la Pompa JL. Bmp2 and Notch cooperate to pattern the embryonic endocardium. Development (2018) 145:163378
    Aguado T, Gutierrez FJ, Aix E, Schneider RP, Giovinnazo G, Blasco MA, Flores I. Telomere length defines the cardiomyocyte differentiation potency of mouse induced pluripotent stem cells. Stem Cells (2017) 35:362-73
    Gomez-Salinero JM, Lopez-Olaneta MM, Ortiz-Sanchez P, Larrasa-Alonso J, Gatto A, Felkin LE, Barton PJ, Navarro-Lerida I, Angel Del Pozo M, Garcia-Pavia P, Sundararaman B, Giovinazo G, Yeo GW, Lara-Pezzi E. The Calcineurin Variant CnAbeta1 Controls Mouse Embryonic Stem Cell Differentiation by Directing mTORC2 Membrane Localization and Activation. Cell Chem Biol (2016) 23:1372-82
    Link to the full text in Repisalud
    Rosello-Diez A, Arques CG, Delgado I, Giovinazzo G and Torres M. Diffusible signals and epigenetic timing cooperate in late proximo-distal limb patterning. Development (2014) 141:1534-43
    Gonzalez-Lazaro M, Rosello-Diez A, Delgado I, Carramolino L, Sanguino MA, Giovinazzo G, Torres M. Two new Targeted alleles for the comprehensive analysis of Meis1 functions in the mouse Genesis (2014) 52:967-75
    Clavería C, Giovinazzo G, Sierra R, Torres M. Myc-driven endogenous cell competition in the early mammalian embryo. Nature (2013) 500:39-44
    Hidalgo-Figueroa M, Bonilla S, Gutiérrez F, Pascual A, López-Barneo J. GDNF is predominantly expressed in the PV+ neostriatal interneuronal ensemble in normal mouse and after injury of the nigrostriatal pathway. J Neurosci (2012) 32:864-72
    Casanova JC, Uribe V, Badia-Careaga C, Giovinazzo G, Torres M, Sanz-Ezquerro JJ. Apical ectodermal ridge morphogenesis in limb development is controlled by Arid3b-mediated regulation of cell movements. Development (2011) 138:1195-205

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