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E.g., 03/02/2023
Cells use two mechanisms to detect force: one gradual and progressive mediated by newly identified large membrane depressions called dolines (left); the other abrupt, activated above a certain threshold, and mediated by minute membrane invaginations called caveolae (right).
Research
23 Dec 2022

A study published in Nature Cell Biology confirms that caveolae are essential for the mechanical responses of tissues subject to large mechanical forces (such as muscle, heart, blood vessels, and fat), whereas larger membrane depressions (termed 'dolines') are important for the response to weak or medium-strength forces

La Dra. Amelia Escolano
About the CNIC
9 Aug 2022

Dr. Amelia Escolano runs her own group in Philadelphia (USA) where she is an Assistant Professor at the Wistar Institute's Center for Vaccines and Immunotherapy

Microfotografía de una monocapa de cardiomiocitos derivados de células madre inducidas a la pluripotencia, representativa de las que se usaron para estudiar los mecanismos de arritmias y el rescate de la función normal por el gen que codifica a la sintrofina-α
Research
29 Jun 2022

Investigadores del CNIC  revelan por primera los mecanismos moleculares que subyacen a las arritmias que ocurren en pacientes que padecen “Distrofia Muscular de Duchenne”

An optical section from a ventral view of a mouse embryo at embryonic day E8.0. The section is overlain with a cast of the three-dimensional shape of the forming heart (red) and the incipient circulatory system (purple).
Research
17 May 2022

The 3D atlas has allowed the scientists to identify the beginning of left–right asymmetry in the heart

Dr. Cristóbal Belda se convirtió en el nuevo Director del Instituto de Salud Carlos III.
Miguel Palomino Segura, Georgiana Crainiciuc, Jon Sicilia y Andrés Hidalgo
Research
5 Jan 2022

Scientists at the CNIC have developed a simple model for studying the behavior of immune cells in live animals and have identified a harmful cell behavior pattern associated with cardiovascular disease


Álvaro Macías, Jesús Vázquez, Pilar Gonzalo, Carla Espinós, Beatriz Dorado, Emilio Camafeita, Vicente Andrés, María J Andrés, Cristina González, Amanda Sánchez, Víctor Fanjul.
Research
26 Oct 2021

Scientists from the CNIC and the CIBERCV have generated the first experimental animal model that develops Hutchinson-Gilford Progeria Syndrome and allows its controlled reversal


About the CNIC
6 Aug 2021

CNIC and the Mario Negri Institute in Milan (Italy) coordinate REBOOT, a project that aims to study whether treatment with beta-blockers is beneficial for patients who have suffered a myocardial infarction

Dra. Sabio
About the CNIC
17 Jun 2021

The jury acknowledged this CNIC researcher's contribution to understanding why obesity causes cardiometabolic diseases.

About the CNIC
8 Jun 2021

Dr Enríquez and Dr del Pozo Muñoz join their colleagues Dr Miguel Torres, Dr Pura Muñoz and Dr Francisco Sánchez Madrid,  bringing to five the number of CNIC members in EMBO