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E.g., 21/04/2024
Carlos Torroja, Jacob F. Bentzon, Paula Nogales, Laura Carramolino, Vanessa Cumbicus, Daniel Morales, Ana Dopazo, Verónica Labrador y Alberto Benguria
Research
1 Feb 2024

A study published in Nature Cardiovascular Research reveals smooth muscle-derived cells as a new target for reducing the size of atherosclerotic plaque. The results open up new avenues for the design of treatments to enhance the beneficial effect of cholesterol-lowering drugs


Representative results from participants showing atherosclerosis progression (left) and regression (disappearance of plaques, right) in arteries of the neck (carotids) and groin (femorals). Each image pair shows the results of the initial study at baseline and the follow-up study of the same artery 6 years later. The images show representative vascular ultrasound images on the right and 3-dimensional reconstructions on the left.
Research
20 Nov 2023

Atherosclerosis, previously believed to be an irreversible progressive disease, can be reversed if risk factors are contolled early enough

Jesús Vázquez, Jacob Fog Bentzon, Emilio Camafeita y Esmeralda Lewis.
About the CNIC
13 Apr 2021

The new insight supports the need to keep both LDL cholesterol and blood pressure low throughout life by healthy diet choices, weight control, exercise, and, when needed, by drug therapy

A cholesterol plaque in a carotid artery, visualized by vascular magnetic resonance imaging.
Research
12 Dec 2017

CNIC researchers have demonstrated that, after age and male sex, LDL-C is the main predictor of the presence of arterial atherosclerotic plaques

3D ultrasound of the right carotid artery. An atherosclerotic plaque is visible as a small protrusion (arrow) in the vessel wall of the internal branch of the proximal carotid artery (bottom), close to the bifurcation. In contrast, the surface of the disease-free external branch (top) is smooth (asterisk).
Research
24 Jul 2017

CNIC researchers show the value of total atherosclerosis burden for the identification of individuals at risk of cardiovascular disease

Ignacio Flores, Juan M. Fernández-Alvira, Valentín Fuster, Vicente Andrés y Beatriz Dorado
Research
24 May 2016

Half of patients with CVD show no above-normal risk of developing the disease on the basis of classical risk factors, such as high cholesterol, smoking, lack of exercise, and high blood pressure