Selected publications

    Benedicto I, Carmona RM, Barettino A, Espinós-Estévez C, Gonzalo P, Nevado RM, de la Fuente-Pérez M, Andrés-Manzano MJ, González-Gómez C, Rolas L, Dorado B, Nourshargh S, Hamczyk MR, Andrés V. Exacerbated atherosclerosis in progeria is prevented by progerin elimination in vascular smooth muscle cells but not endothelial cells. doi:10.1073/pnas.2400752121. Proc Natl Acad Sci U S A (2024) 121:e2400752121
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    Díez-Díez M, Amorós-Pérez M, de la Barrera J, Vázquez E, Quintas A, Pascual-Figal DA, Dopazo A, Sánchez-Cabo F, Kleinman ME, Gordon LB, Fuster V, Andrés V*, Fuster JJ* *co-corresponding authors Clonal hematopoiesis is not prevalent in Hutchinson-Gilford progeria syndrome. doi: 10.1007/s11357-022-00607-2. Geroscience (2023) 45:1231-1236
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    Macías Á, Díaz-Larrosa JJ, Blanco Y, Fanjul V, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, da Rocha AM, Ponce-Balbuena D, Allan A, Filgueiras-Rama D, Jalife J, Andrés V Paclitaxel mitigates structural alterations and cardiac conduction system defects in a mouse model of Hutchinson-Gilford progeria syndrome Cardiovasc Res (2022) 118:503-516
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    Sánchez-López A, Espinós-Estévez C, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, Fanjul V, Riquelme-Borja R, Hamczyk MR, Macías Á, Del Campo L, Camafeita E, Vázquez J, Barkaway A, Rolas L, Nourshargh S, Dorado B, Benedicto I, Andrés V Cardiovascular Progerin Suppression and lamin A Restoration Rescues Hutchinson-Gilford Progeria Syndrome Circulation (2021) 144:1777-1794
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    Hamczyk MR, Nevado RM, Barettino A, Fuster V, Andres V Biological Versus Chronological Aging: JACC Focus Seminar J Am Coll Cardiol (2020) 75:919-930
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    Fanjul V, Jorge I, Camafeita E, Macías Á, González-Gómez C, Barettino A, Dorado B, Andrés-Manzano MJ, Rivera-Torres J, Vázquez J, López-Otín C, Andrés V Identification of common cardiometabolic alterations and deregulated pathways in mouse and pig models of aging Aging Cell (2020) 19:e13203
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    Hamczyk MR, Villa-Bellosta R, Quesada V, Gonzalo P, Vidak S, Nevado RM, Andrés-Manzano MJ, Misteli T, López-Otín C, Andrés V. Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle cells. EMBO Mol Med (2019) 11:e9736
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    Del Campo L*, Sanchez-Lopez A*, Salaices M, von Kleeck RA, Exposito E, Gonzalez-Gomez C, Cusso L, Guzman-Martinez G, Ruiz-Cabello J, Desco M, Assoian RK, Briones AM, Andres V. (LDC and ASL contributed equally) Vascular smooth muscle cell-specific progerin expression in a mouse model of Hutchinson-Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite. Aging Cell (2019) 18:e12936
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    Hamczyk MR, Villa-Bellosta R, Gonzalo P, Andres-Manzano MJ, Nogales P, Bentzon JF, Lopez-Otin C, Andres V. Vascular Smooth Muscle-Specific Progerin Expression Accelerates Atherosclerosis and Death in a Mouse Model of Hutchinson-Gilford Progeria Syndrome. Circulation (2018) 138:266-82
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    Hamczyk MR, Del Campo L, Andres V. Aging in the Cardiovascular System: Lessons from Hutchinson-Gilford Progeria Syndrome. Annu Rev Physiol (2018) 80:27-48
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    Fernández-Alvira JM, Fuster V, Dorado B, Soberón N, Flores I, Gallardo M, Pocock S, Blasco MA, Andrés V. Short Telomere Load, Telomere Length, and Subclinical Atherosclerosis: The PESA Study. J Am Coll Cardiol (2016) 67:2467-76
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    Rivera-Torres J, Calvo CJ, Llach A, Guzman-Martinez G, Caballero R, Gonzalez-Gomez C, Jimenez-Borreguero LJ, Guadix JA, Osorio FG, Lopez-Otin C, Herraiz-Martinez A, Cabello N, Vallmitjana A, Benitez R, Gordon LB, Jalife J, Perez-Pomares JM, Tamargo J, Delpon E, Hove-Madsen L, Filgueiras-Rama D, Andres V. Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations. Proc Natl Acad Sci U S A (2016) 113:E7250–9
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    Chèvre R, González-Granado JM, Megens RT, Sreeramkumar V, Silvestre-Roig C, Molina-Sanchez P, Weber C, Soehnlein O, Hidalgo A*, Andrés V* (VA and AH contributed equally). High-Resolution Imaging of Intravascular Atherogenic Inflammation in Live Mice. Circ Res (2014) 114:770-9
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    Villa-Bellosta R, Rivera J, Osorio FG, Acín-Pérez R, Enríquez JA, López-Otín C, Andrés V. Defective Extracellular Pyrophosphate Metabolism Promotes Vascular Calcification in a Mouse Model of Hutchinson-Gilford Progeria Syndrome that is Ameliorated upon Pyrophosphate Treatment. Circulation (2013) 127:2442-51
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    González-Navarro H, Vinué A, Sanz MJ, Delgado M, Pozo MA, Serrano M, Burks DJ, Andrés V. Increased dosage of Ink4/Arf protects against glucose intolerance and insulin resistance associated with aging Aging Cell (2013) 12:102-11
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    Fuster JJ, González-Navarro H, Vinué A, Molina P, Andrés-Manzano MJ, Nakayama KI, Nakayama K, Díez-Juan A, Bernad A, Rodríguez C, Martínez-González J, Andrés V. Deficient p27 Phosphorylation at Serine 10 Increases Macrophage Foam Cell Formation and Aggravates Atherosclerosis Through a Proliferation-Independent Mechanism. Arterioscler Thromb Vasc Biol (2011) 31:2455-2463
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    González-Navarro H, Abu Nabah Y, Vinué A, Andrés-Manzano MJ, Collado M, Serrano M, Andrés V. p19(ARF) Deficiency Reduces Macrophage and Vascular Smooth Muscle Cell Apoptosis and Aggravates Atherosclerosis. J Am Coll Cardiol (2010) 55:2258-68
    Andres V, Gonzalez JM. Role of A-type lamins in signaling, transcription, and chromatin organization J Cell Biol (2009) 187:945-57
    González JM, Navarro-Puche A, Casar B, Crespo P, Andrés V. Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope. J Cell Biol (2008) 183:653-66
    Ivorra C, Kubicek M, González JM, Sanz-González SM, Alvarez-Barrientos A, O'Connor JE, Burke B, Andrés V. A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C. Genes Dev (2006) 20:307-20

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