Selected publications

Bartolome-Izquierdo N, De Yebenes VG, Alvarez-Prado AF, Mur SM, Lopez JA, Roa S, Vazquez J, Ramiro AR. miR-28 regulates the germinal center reaction and blocks tumor growth in preclinical models of non-Hodgkin lymphoma. Blood (2017) 129:2408-19
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Binek A, Fernandez-Jimenez R, Jorge I, Camafeita E, Lopez JA, Bagwan N, Galan-Arriola C, Pun A, Aguero J, Fuster V, Ibanez B, Vazquez J. Proteomic footprint of myocardial ischemia/reperfusion injury: Longitudinal study of the at-risk and remote regions in the pig model. Sci Rep (2017) 7:12343
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Latorre-Pellicer A, Moreno-Loshuertos R, Lechuga-Vieco AV, Sánchez-Cabo F, Torroja C, Acín-Pérez R, Calvo E, Aix E, González-Guerra A, Logan A, Bernad-Miana ML, Romanos E, Cruz R, Cogliati S, Sobrino B, Carracedo Á, Pérez-Martos A, Fernández-Silva P, Ruíz-Cabello J, Murphy MP, Flores I, Vázquez J, Enríquez JA. Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing. Nature (2016) 525:561-65
Cogliati S*, Calvo E*, Loureiro M, Guaras AM, Nieto-Arellano R, Garcia-Poyatos C, Ezkurdia I, Mercader N, Vazquez J*, Enriquez JA* (SC and EC contributed equally; JV and JAE are co-corresponding authors) Mechanism of super-assembly of respiratory complexes III and IV. Nature (2016) 539:579-82
Cibrian D, Saiz ML, de la Fuente H, Sanchez-Diaz R, Moreno-Gonzalo O, Jorge I, Ferrarini A, Vazquez J, Punzon C, Fresno M, Vicente-Manzanares M, Dauden E, Fernandez-Salguero PM, Martin P, Sanchez-Madrid F. CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis. Nat Immunol (2016) 17:985-96
Osorio FG, Soria-Valles C, Santiago-Fernandez O, Bernal T, Mittelbrunn M, Colado E, Rodriguez F, Bonzon-Kulichenko E, Vazquez J, Porta-de-la-Riva M, Ceron J, Fueyo A, Li J, Green AR, Freije JM, Lopez-Otin C. Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling. Nat Med (2016) 22:91-6
Calvo E, Garcia-Alvarez A, Vazquez J. The Quest for Metabolic Biomarkers of Pulmonary Hypertension. J Am Coll Cardiol (2016) 67:190-2
Gonzalez-Teran B, Lopez JA, Rodriguez E, Leiva L, Martinez-Martinez S, Bernal JA, Jimenez-Borreguero LJ, Redondo JM, Vazquez J, Sabio G. p38gamma and delta promote heart hypertrophy by targeting the mTOR-inhibitory protein DEPTOR for degradation. Nat Commun (2016) 7:10477
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Blas-Rus N, Bustos-Moran E, Perez de Castro I, de Carcer G, Borroto A, Camafeita E, Jorge I, Vazquez J, Alarcon B, Malumbres M, Martin-Cofreces NB, Sanchez-Madrid F. Aurora A drives early signalling and vesicle dynamics during T-cell activation. Nat Commun (2016) 7:11389
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García-Marqués F, Trevisan-Herraz M, Martínez-Martínez S, Camafeita E, Jorge I, Lopéz JA, Méndez-Barbero N, Méndez-Ferrer S, Del Pozo MÁ, Ibáñez B, Andrés V, Sánchez-Madrid F, Redondo JM, Bonzon-Kulichenko E, Vázquez J. A novel systems-biology algorithm for the analysis of coordinated protein responses using quantitative proteomics Mol Cell Proteomics (2016) 15:1740-60
Guaras A, Perales-Clemente E, Calvo E, Acin-Perez R, Loureiro-Lopez M, Pujol C, Martinez-Carrascoso I, Nunez E, Garcia-Marques F, Rodriguez-Hernandez MA, Cortes A, Diaz F, Perez-Martos A, Moraes CT, Fernandez-Silva P, Trifunovic A, Navas P, Vazquez J, Enriquez JA. The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency. Cell Rep (2016) 15:197-209
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Burillo E, Jorge I, Martinez-Lopez D, Camafeita E, Blanco-Colio LM, Trevisan-Herraz M, Ezkurdia I, Egido J, Michel JB, Meilhac O, Vazquez J, Martin-Ventura JL. Quantitative HDL Proteomics Identifies Peroxiredoxin-6 as a Biomarker of Human Abdominal Aortic Aneurysm. Sci Rep (2016) 6:38477
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Bonzon-Kulichenko E, Garcia-Marques F, Trevisan-Herraz M, Vazquez J. Revisiting Peptide Identification by High-Accuracy Mass Spectrometry: Problems Associated with the Use of Narrow Mass Precursor Windows J Proteome Res (2015) 14:700-10
Ezkurdia I, Juan D, Rodriguez JM, Frankish A, Diekhans M, Harrow J, Vazquez J, Valencia A, Tress ML Multiple evidence strands suggest that there may be as few as 19,000 human protein-coding genes Hum Mol Genet (2014) 23:5866-78
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Ruiz-Meana M*, Nunez E*, Miro-Casas E, Martinez-Acedo P, Barba I, Rodriguez-Sinovas A, Inserte J, Fernandez-Sanz C, Hernando V, Vazquez J*, Garcia-Dorado D* (MRM and EN contributed equally; JV and DGD co-corresponding authors) Ischemic preconditioning protects cardiomyocyte mitochondria through mechanisms independent of cytosol. J Mol Cell Cardiol (2014) 68:79-88
Navarro P*, Trevisan-Herraz M*, Bonzon-Kulichenko E*, Nunez E, Martinez-Acedo P, Perez-Hernandez D, Jorge I, Mesa R, Calvo E, Carrascal M, Hernaez ML, Garcia F, Barcena JA, Ashman K, Abian J, Gil C, Redondo JM and Vazquez J (PN, MTH and EBK contributed equally) General Statistical Framework for Quantitative Proteomics by Stable Isotope Labeling. J Proteome Res (2014) 13:1234-47
Ezkurdia I, Vazquez J, Valencia A, Tress M Analyzing the First Drafts of the Human Proteome J Proteome Res (2014) 13:3854-5
Jorge I, Burillo E, Mesa R, Baila-Rueda L, Moreno M, Trevisan-Herraz M, Silla-Castro JC, Camafeita E, Ortega-Muñoz M, Bonzon-Kulichenko E, Calvo I, Cenarro A, Civeira F, Vázquez J The human HDL proteome displays high inter-individual variability and is altered dynamically in response to angioplasty-induced atheroma plaque rupture J Proteomics (2014) 106C:61-73
Villarroya-Beltri C, Gutiérrez-Vázquez C, Sánchez-Cabo F, Pérez-Hernández D, Vázquez J, Martin-Cofreces N, Martinez-Herrera DJ, Pascual-Montano A, Mittelbrunn M*, Sánchez-Madrid F* (MM and FSM contributed equally) Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs. Nat Commun (2013) 4:2980
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Martinez-Acedo P, Nunez E, Sanchez-Gomez FJ, Moreno M, Ramos E, Izquierdo-Alvarez A, Miro-Casas E, Mesa R, Rodriguez P, Martinez-Ruiz A, Garcia-Dorado D, Lamas S, Vazquez J. GELSILOX: a novel strategy for global analysis of the dynamic thiol redox proteome Mol Cell Proteomics (2012) 11:800-13