Image of a mouse zygote Image 1a. Image of a mouse zygote.

Image of a mouse zygote ready to be microinjected Image 1b. Image of a mouse zygote ready to be microinjected.

Mouse blastocyst injected with modified mouse embryonic stem cells Image 2. Mouse blastocyst injected with modified mouse embryonic stem cells.

Image of a 6.5 day post coital embryo (6.5 dpc) in a microinjection session with Cre-recombinase Image 4A. Image of a 6.5 day post coital embryo (6.5 dpc) in a microinjection session with Cre-recombinase.

Detail of the injection site of a 6.5-day post-coital embryo (6.5 dpc) in a microinjection session with Cre-recombinase Image 3B. Detail of the injection site of a 6.5-day post-coital embryo (6.5 dpc) in a microinjection session with Cre-recombinase.

Mouse sperm detail Image 4A. Mouse sperm detail.

Mouse oocyte In Vitro Fertilization Image 4B. Mouse oocyte In Vitro Fertilization (IVF).
The vast majority of these sperm will disappear when we isolate the oocyte for culture.
Only one will reach the goal.


Video 1. Sequence of a pronuclear microinjection session in mouse zygotes.


Video 2. Sequence of a microinjection session of mouse blastocysts with embryonic stem cells.


Video 3. Sequence of a mouse Intracytoplasmic Sperm Injection (ICSI) session.