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E.g., 28/03/2024
E.g., 28/03/2024
Mercedes Ricote, María Piedad Menéndez-Gutiérrez,  Jesús Porcuna,  Ana Paredes, Vanessa Núñez e Irene Calero.
Research
15 Dec 2022

A CNIC team has shown that the  retinoid and unsaturated fatty acid sensor RXR is a key protein in the maintenance of a balanced production of the different types of blood cells

Fibroblasto embrionario murino Cav1KO (izquierda, sin caveolas) muestra un mayor reclutamiento de integrina beta 1 activa (magenta) en torno a bolitas recubiertas con fibronectina, en comparación con un fibroblasto embrionario murino Cav1WT (derecha, con caveolas).
Research
13 Dec 2022

A new study published in eLife shows that small cups or nanofolds on the cell membrane called caveolae, by limiting abrupt changes in membrane tension, regulate the number and activity of mechanical microsensors on the cell surface called integrins

Transverse heart sections from wild type mice (WT) and transgenic mice overexpressing beta-3 adrenergic receptor in cardiomyocytes (c-h3tg) after 3 months of aortic stenosis (transaortic constriction, TAC) or control (sham). Hypertrophy after TAC was less severe in the transgenic mice
Research
29 Nov 2022

The experimental study, led by researchers at the CNIC, shows that boosting the expression of this adrenalin receptor in heart cells improves mitochondrial function in the heart

Cellular and Molecular Sciences: Describen un nuevo mecanismo que relaciona la inflamación y el remodelado cardiovascular patológico
About the CNIC
23 Aug 2022

The finding provides a basis for mitigating the loss of muscle regenerative capacity in elderly people

Embrión de ratón con el gen Hoxb1 expresado de forma normal (izquierda) y embrión de ratón donde se expresa fuera de lugar (derecha) por la acción de Oct4
Una cámara térmica muestra el efecto de la IL-12 sobre la grasa parda en ratón.
Research
9 Jun 2022

A study published in Hepatology demonstrates that the activation of thermogenesis in the livers of obese mice contributes to weight loss and improves diabetes symptoms

Macaca
Research
18 Apr 2022

The research will provide insights into the development of potential treatments for neurological diseases and obesity, among other human conditions


María García García, Miguel Ángel del Pozo Barriuso, Sara Sánchez Perales, Laura Sotodosos-Alonso, Enrique Calvo, Jesús Vázquez y Asier Echarri
Research
3 Mar 2022

Most biological processes require the import to the cell nucleus of key regulatory factors; one of the most important of these factors is the protein YAP

José Javier Fuster
About the CNIC
23 Feb 2022

Researchers from the CNIC and Columbia University (USA) review the role of acquired mutations and clonal hematopoiesis in cardiovascular disease