The AIU has the following equipment:

  • High-resolution PET/CT nanoPET (Mediso)
  • Small animal magnetic resonance scanner 7 Tesla (Varian)
  • Two in vivo optical imaging systems: 200 XENOGEN (IVIS, PerkinElemer) and FMT 1500 (Visian Medical)
  • Intravital microscope (Intelligent imaging)
  • Ultrasound systems (2 x VEVO 2100, Visualsonics)
  • Radiopharmaceutical Unit for in situ production of molecular probes with different radioisotopes (18F, 89Zr, 68Ga, etc.).
  • The type of studies that can be done covers a wide range of possibilities:
  • Magnetic resonance: high-resolution 'conventional' anatomical image, spectroscopy, angiography, tissue perfusion, magnetization transfer, cardiac dynamic studies, etc.
  • Computed tomography imaging: bone and biomaterial studies, morphometric, pulmonary, etc.
  • Nuclear imaging: cell metabolism studies by glucose (18F-FDG) or palmitic acid (18F-FTHA), with applications in oncology, neurology, cardiology and inflammatory and infectious diseases. In vivo monitoring of biomolecules (antibodies/peptides), cell tracking, etc.
  • Molecular probes: synthesis of nanoparticles and/or radioactive or fluorescent marking of different biomolecules (antibodies, peptides, microvesticles, etc.).
  • In vivo optical imaging: cell metabolism studies (genetically modified cells), cell monitoring, etc.
  • Echocardiographic studies: in rodents and zebrafish, fetal studies in rodents, vascular ultrasound, etc.
  • Other services provided by the laboratory include advice on optimal techniques for a specific problem and data post-processing (including quantification, co-registration of modalities, parametric statistical analysis -SPM-, etc.).





  • Cardiac functionality (EF, mitral flow, myocardial mass, etc.)
  • Abdominal Aorta
  • Zebra fish


  • Echo-guided tap
  • Femoral studies

Detailed (Also includes a basic study)

  • Right Ventricle
  • Hypertension
  • Valvulopathy
  • Carotid Artery
  • Diastolic function (pulmonary veins and tissuer Doppler)
  • Coronary arteries
  • Fetus
  • Thoracic Aorta (cardiac outflow, aortic arch, root, ring, descending aorta, ascending aorta, root, annulus, etc.)



  • Neurology
  • Abdominal anatomy
  • Cardiology
  • Oncology
  • Adipose tissue
  • Angiography


  • Cardiology
  • Funtional MRI (Aparent Diffusion Coefficient and Diffusion Tensor Imaging)


  • DSC (It needs gadolinium contrast agent)
  • ASL

Parametric maps T1/ T2 /T2*

  • Absolute Quantitative Data

Spectroscopy (13C, 1H, 31P)

  • Chemical composition
  • Adipose tissues percentage vs. water


18F-FDG (glucose metabolism)

  • Neurology
  • Cardiology
  • Inflammation Oncology
  • Radiochemistry



  • Bones anatomy
  • Soft tissue visualization (implies contrast agent administration)
  • Adipose tissue distribution


  • Lung edema evolution


Gallium-68 Radiochemistry 68Ga-DOTA

  • Perfusion

Gallium-68 Radiochemistry 68Ga-DOTATATE

  • Somatostatin receptors. Oncology/ Cardiology

Gallium-68 Radiochemistry 68Ga-DOTARGD2

  • Integrin receptor Oncology/Cardiology

Fluorine-18 Radiochemistry 18FTHA

  • Fatty acids metabolism (FTHA)

Antibodies radiolabeling 68Ga or 89Zr

  • Antibodies biodistribution. Cardiology, oncology and immunology

Intravital Microscopy

Calvarial bone marrow

Cremaster muscle

Tibial and plantar muscle




  • Microvascular diameter
  • Skeletal muscle morphology
  • Anatomy of the microvascular network of the bone marrow
  • Leukocyte interactions during the steps of the infiltration process: rolling over the vascular endothelium, firm adhesion, crawling and extravasation
  • Quantification of neutrophil platelet interactions
  • Interactions of satellite cells with macrophages, endothelium, muscle fiber etc. (2D and 3D images)
  • Evolution of the inflammation process, Acute Lung Damage, alveolocapillary permeability and tissue repair in microcirculation and/or tissue, etc.
  • Microvascular Hemodynamics: average blood flow speed
  • Kinetic parameters of neutrophils on vascular endothelium and extravascular space (speed, directionality, cumulative distance and Euclidean distance)
  • Clot formation
  • NETs

Most of the facilities and imaging techniques described are also available to external users through the ICTS "Distributed Biomedical Imaging Network" (